Atherosclerosis induced by a high-cholesterol and high-fat diet in the inbred strain of the Wuzhishan miniature pig

Y Zhao, L Xiang, Y Liu, M Niu, J Yuan… - Animal …, 2018 - Taylor & Francis
Coronary artery disease has a significant genetic predisposition, which mainly results from
atherosclerosis. Miniature pig is an excellent model to investigate atherosclerosis. This study
investigated whether the occurrence and development of atherosclerosis in the Wuzhishan
miniature pigs (WZSPs) that were closely bred 12 generations had better consistency. The
WZSPs (n= 9) were fed a high-cholesterol and high-fat diet (HCFD). After continuous
feeding, 3 WZSPs each were sacrificed at 6, 8, and 12 months, respectively, and the general …

Atherosclerosis induced by a high-cholesterol and high-fat diet in the inbred strain of the Wuzhishan miniature pig.

ZYQ Zhao YuQiong, XL Xiang Lei, LYQ Liu YaQian… - 2018 - cabidigitallibrary.org
Coronary artery disease has a significant genetic predisposition, which mainly results from
atherosclerosis. Miniature pig is an excellent model to investigate atherosclerosis. This study
investigated whether the occurrence and development of atherosclerosis in the Wuzhishan
miniature pigs (WZSPs) that were closely bred 12 generations had better consistency. The
WZSPs (n= 9) were fed a high-cholesterol and high-fat diet (HCFD). After continuous
feeding, 3 WZSPs each were sacrificed at 6, 8, and 12 months, respectively, and the general …
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